chr8:37823798:A>G Detail (hg19) (ADRB3)

Information

Genome

Assembly Position
hg19 chr8:37,823,798-37,823,798
hg38 chr8:37,966,280-37,966,280 View the variant detail on this assembly version.

HGVS

Type Transcript Protein
RefSeq NM_000025.2:c.190T>C NP_000016.1:p.Trp64Arg
Ensemble ENST00000345060.5:c.190T>C ENST00000345060.5:p.Trp64Arg
Summary

MGeND

Clinical significance
Variant entry
GWAS entry
Disease area statistics Show details

Frequency

JP HGVD:0.178
ToMMo:0.192
NCBN:[No Data.]
NCBN(Hondo):[No Data.]
NCBN(Ryukyu):[No Data.]
East asia ExAC:0.144

Prediction

ClinVar

Clinical Significance Benign
Review star
Show details
Links
Type Database ID Link
Gene MIM 109691 OMIM
HGNC 288 HGNC
Ensembl ENSG00000188778 Ensembl
NCBI NCBI
Gene Cards Gene Cards
OncoKB OncoKB
Type Database ID Link
Variant TogoVar tgv32815651 TogoVar
COSMIC
MONDO
Disease area statistics
[No Data.]
MGeND
[No Data.]
ClinVar
Clinical significance Last evaluated Review status Condition Origin Links
risk factor 2004-10-01 no assertion criteria provided obesity germline Detail
Benign 2021-06-09 criteria provided, single submitter not provided germline Detail
CIViC
[No Data.]
DisGeNET
Score Disease name Description Source Pubmed Links
0.343 obesity Several common single nucleotide polymorphisms (SNPs) including Gly389Arg in bet... BeFree 17611309 Detail
0.335 obesity Several common single nucleotide polymorphisms (SNPs) including Gly389Arg in bet... BeFree 17611309 Detail
0.151 obesity Several common single nucleotide polymorphisms (SNPs) including Gly389Arg in bet... BeFree 17611309 Detail
0.231 obesity We analyzed the obesity-related phenotypes body mass index (BMI), percentage of ... BeFree 15959859 Detail
0.343 obesity We analyzed the obesity-related phenotypes body mass index (BMI), percentage of ... BeFree 15959859 Detail
0.440 obesity We analyzed the obesity-related phenotypes body mass index (BMI), percentage of ... BeFree 15959859 Detail
0.335 obesity We analyzed the obesity-related phenotypes body mass index (BMI), percentage of ... BeFree 15959859 Detail
0.223 obesity We analyzed the obesity-related phenotypes body mass index (BMI), percentage of ... BeFree 15959859 Detail
0.439 obesity We analyzed the obesity-related phenotypes body mass index (BMI), percentage of ... BeFree 15959859 Detail
0.309 obesity We analyzed the obesity-related phenotypes body mass index (BMI), percentage of ... BeFree 15959859 Detail
0.330 Diabetes Mellitus, Non-Insulin-Dependent Under an additive genetic model, the C allele of ADRB3-rs4994, the C allele of E... BeFree 22391941 Detail
0.287 Diabetes Mellitus, Non-Insulin-Dependent Under an additive genetic model, the C allele of ADRB3-rs4994, the C allele of E... BeFree 22391941 Detail
0.079 Diabetes Mellitus, Non-Insulin-Dependent Under an additive genetic model, the C allele of ADRB3-rs4994, the C allele of E... BeFree 22391941 Detail
0.004 pancreatic carcinoma We genotyped 7 single-nucleotide polymorphisms (SNPs) in PPARG2 (rs1801282), ADI... BeFree 25516658 Detail
<0.001 pancreatic carcinoma We genotyped 7 single-nucleotide polymorphisms (SNPs) in PPARG2 (rs1801282), ADI... BeFree 25516658 Detail
<0.001 pancreatic carcinoma We genotyped 7 single-nucleotide polymorphisms (SNPs) in PPARG2 (rs1801282), ADI... BeFree 25516658 Detail
<0.001 Malignant neoplasm of pancreas We genotyped 7 single-nucleotide polymorphisms (SNPs) in PPARG2 (rs1801282), ADI... BeFree 25516658 Detail
<0.001 Malignant neoplasm of pancreas We genotyped 7 single-nucleotide polymorphisms (SNPs) in PPARG2 (rs1801282), ADI... BeFree 25516658 Detail
<0.001 Malignant neoplasm of pancreas We genotyped 7 single-nucleotide polymorphisms (SNPs) in PPARG2 (rs1801282), ADI... BeFree 25516658 Detail
0.003 Malignant neoplasm of pancreas We genotyped 7 single-nucleotide polymorphisms (SNPs) in PPARG2 (rs1801282), ADI... BeFree 25516658 Detail
<0.001 pancreatic carcinoma We genotyped 7 single-nucleotide polymorphisms (SNPs) in PPARG2 (rs1801282), ADI... BeFree 25516658 Detail
<0.001 Malignant neoplasm of pancreas We genotyped 7 single-nucleotide polymorphisms (SNPs) in PPARG2 (rs1801282), ADI... BeFree 25516658 Detail
<0.001 pancreatic carcinoma We genotyped 7 single-nucleotide polymorphisms (SNPs) in PPARG2 (rs1801282), ADI... BeFree 25516658 Detail
0.125 Hyperlipidemia In conclusion, no major difference was associated with the beta3AR Trp64Arg or F... BeFree 11699048 Detail
0.079 Diabetes Mellitus, Non-Insulin-Dependent In conclusion, no major difference was associated with the beta3AR Trp64Arg or F... BeFree 11699048 Detail
0.049 Diabetes Mellitus, Non-Insulin-Dependent In conclusion, no major difference was associated with the beta3AR Trp64Arg or F... BeFree 11699048 Detail
<0.001 Hyperlipidemia In conclusion, no major difference was associated with the beta3AR Trp64Arg or F... BeFree 11699048 Detail
0.012 essential hypertension These data demonstrated that ADRB3 rs4994 and CYP11B2 rs1799998 were significant... BeFree 25099490 Detail
0.001 essential hypertension These data demonstrated that ADRB3 rs4994 and CYP11B2 rs1799998 were significant... BeFree 25099490 Detail
0.029 Metabolic syndrome X We investigated whether the -3826A/G polymorphism (rs1800592) of the uncoupling ... BeFree 24138564 Detail
0.004 Metabolic syndrome X We investigated whether the -3826A/G polymorphism (rs1800592) of the uncoupling ... BeFree 24138564 Detail
0.029 Metabolic syndrome X The objective of this work was to analyze the association of polymorphisms in AD... BeFree 24972470 Detail
<0.001 Metabolic syndrome X The objective of this work was to analyze the association of polymorphisms in AD... BeFree 24972470 Detail
0.079 Diabetes Mellitus, Non-Insulin-Dependent The ADRB3 Trp64Arg variant is a susceptibility gene polymorphism for T2D and the... BeFree 24972470 Detail
<0.001 Diabetes Mellitus, Non-Insulin-Dependent The ADRB3 Trp64Arg variant is a susceptibility gene polymorphism for T2D and the... BeFree 24972470 Detail
0.079 Diabetes Mellitus, Non-Insulin-Dependent We studied possible relations between GDM and both insulin receptor substrate 1 ... BeFree 17046546 Detail
0.003 gestational diabetes We studied possible relations between GDM and both insulin receptor substrate 1 ... BeFree 17046546 Detail
0.003 gestational diabetes The other polymorphisms studied were not significantly associated with gestation... BeFree 17342473 Detail
0.220 gestational diabetes The other polymorphisms studied were not significantly associated with gestation... BeFree 17342473 Detail
<0.001 gestational diabetes The other polymorphisms studied were not significantly associated with gestation... BeFree 17342473 Detail
0.343 obesity Beta3AR Trp64Arg and PPARgamma2 Pro12Ala polymorphisms might be associated with ... BeFree 17624182 Detail
0.007 gestational diabetes The other polymorphisms studied were not significantly associated with gestation... BeFree 17342473 Detail
0.439 obesity Beta3AR Trp64Arg and PPARgamma2 Pro12Ala polymorphisms might be associated with ... BeFree 17624182 Detail
<0.001 gestational diabetes The other polymorphisms studied were not significantly associated with gestation... BeFree 17342473 Detail
0.003 schizophrenia Possible impact of ADRB3 Trp64Arg polymorphism on BMI in patients with schizophr... BeFree 22609474 Detail
0.017 Cardiovascular Diseases The β3-adrenoceptor (ADRB3) gene Trp64Arg polymorphism has been shown to be asso... BeFree 22609474 Detail
0.079 Diabetes Mellitus, Non-Insulin-Dependent Some studies indicate that the Trp64Arg polymorphism in the gene encoding the be... BeFree 17852419 Detail
0.006 Obesity, Abdominal The Trp64Arg allele of the beta 3-adrenergic receptor is associated with abdomin... BeFree 7609751 Detail
0.343 obesity Our results suggest that obese postmenopausal women who are heterozygous for the... BeFree 9814483 Detail
0.047 Hypertensive disease In this study, the prevalence of the Trp64Arg ADRB3 polymorphism in a large grou... BeFree 17626108 Detail
0.343 obesity Lack of association between the Trp64 Arg mutation in the beta 3-adrenergic rece... BeFree 9100608 Detail
0.003 cholelithiasis Our results indicate that the ADRB3 Trp64Arg polymorphism is associated with gal... BeFree 17640319 Detail
<0.001 Microvascular Angina The Trp64Arg mutation of the beta 3-adrenergic receptor (beta 3AR) is prevalent ... BeFree 9112025 Detail
0.029 Metabolic syndrome X Relationship between Trp64Arg mutation in the β3-adrenergic receptor gene and me... BeFree 21034552 Detail
0.002 Overactive Bladder The association between the tryptophan 64 arginine polymorphism in the beta(3)-A... BeFree 17600372 Detail
0.029 Metabolic syndrome X The Trp64Arg polymorphism of the beta 3-Adrenergic receptor gene. Lack of associ... BeFree 9250462 Detail
0.003 Metabolic Diseases Our results suggest that the Trp64Arg mutation is not a major determinant of met... BeFree 11213599 Detail
0.343 obesity In summary, we found that obese postmenopausal women who carry the Trp64Arg vari... BeFree 12037740 Detail
0.374 Diabetes Mellitus, Non-Insulin-Dependent The Trp64Arg allele of the beta 3-adrenergic receptor is associated with abdomin... BeFree 7609751 Detail
0.079 Diabetes Mellitus, Non-Insulin-Dependent The β3-adrenoceptor (ADRB3) gene Trp64Arg polymorphism has been shown to be asso... BeFree 22609474 Detail
0.343 obesity The tryptophan to arginine change in position 64 (Trp64Arg) polymorphism of the ... BeFree 16634992 Detail
<0.001 Unipolar Depression We obtained no evidence for the association of ADRB3 Trp64Arg with the developme... BeFree 22609474 Detail
0.079 Diabetes Mellitus, Non-Insulin-Dependent The Trp64Arg polymorphism of the beta 3-Adrenergic receptor gene. Lack of associ... BeFree 9250462 Detail
0.343 obesity The aim of our study was to investigate the interaction of tryptophan-to-arginin... BeFree 22774401 Detail
0.343 obesity It has been shown that the β3-adrenergic receptor (β3-AR) gene Trp64Arg mutation... BeFree 21034552 Detail
<0.001 major depressive disorder We obtained no evidence for the association of ADRB3 Trp64Arg with the developme... BeFree 22609474 Detail
0.343 obesity The beta(3)-adrenergic receptor gene (BAR-3) allelic variant (Trp64Arg and Arg64... BeFree 12943691 Detail
0.002 Overactive Bladder The relationship between the Trp 64 Arg polymorphism of the beta 3-adrenoceptor ... BeFree 21529759 Detail
0.002 Overactive Bladder As the presence of a Trp64Arg polymorphism of the gene encoding the β(3)-adrenoc... BeFree 22972489 Detail
0.001 Dyslipidemias In conclusion, the Trp64Arg polymorphism of the beta 3-adrenergic receptor gene ... BeFree 17087055 Detail
0.079 Diabetes Mellitus, Non-Insulin-Dependent These data suggest that the Trp64Arg mutation not only contributes to weight gai... BeFree 8721782 Detail
0.047 Hypertensive disease To determine whether this SNP affects insulin resistance syndrome associated wit... BeFree 12965109 Detail
0.005 Malignant neoplasm of breast To determine if a missense change at codon 64 of ADRB3 (Trp64Arg), a candidate o... BeFree 17264845 Detail
0.343 obesity Genotype Arg/Arg, but not Trp/Arg, of the Trp64Arg polymorphism of the beta(3)-a... BeFree 11522702 Detail
0.005 diabetic retinopathy The Trp64Arg allele of the beta 3-AR gene was significantly more frequent in the... BeFree 9313761 Detail
0.008 Obesity, Morbid Gender effect of the Trp64Arg mutation in the beta 3 adrenergic receptor gene on... BeFree 9416435 Detail
0.047 Hypertensive disease Our results are consistent with the thesis that the Trp64Arg polymorphism of the... BeFree 10100091 Detail
0.008 Obesity, Morbid Additive effect of A--&gt;G (-3826) variant of the uncoupling protein gene and t... BeFree 8968850 Detail
0.003 cholecystolithiasis Our results indicate that the ADRB3 Trp64Arg polymorphism is associated with gal... BeFree 17640319 Detail
0.079 Diabetes Mellitus, Non-Insulin-Dependent We have investigated whether the Trp64Arg polymorphism of the beta 3-AR was asso... BeFree 9426386 Detail
0.079 Diabetes Mellitus, Non-Insulin-Dependent Effect of the combination of the variants -75G/A APOA1 and Trp64Arg ADRB3 on the... BeFree 17727676 Detail
0.003 interstitial cystitis We analyzed 5 gene polymorphisms (G404781T, Arg16Gly, Trp64Arg, C589T and Ile50V... BeFree 12442007 Detail
0.003 Coronary Arteriosclerosis Beta 3 adrenergic receptor Trp64Arg polymorphism and manifestation of coronary a... BeFree 16715838 Detail
0.343 obesity In conclusion, the Trp64Arg polymorphism of the beta 3-adrenergic receptor gene ... BeFree 17087055 Detail
0.343 obesity Trp64Arg polymorphism of the beta 3-adrenergic receptor gene is associated with ... BeFree 10502846 Detail
0.079 Diabetes Mellitus, Non-Insulin-Dependent In conclusion, the frequency of the Trp64Arg mutation of the beta 3-AR was highe... BeFree 9315379 Detail
<0.001 Ovarian Diseases In the crude analysis, hypothesis tests and odds ratios show that there is no ev... BeFree 15670186 Detail
0.168 Impaired glucose tolerance Trp64Arg mutation of beta 3-adrenergic receptor and insulin sensitivity in subje... BeFree 9313101 Detail
0.343 obesity To investigate the association between the Trp64Arg beta3-adrenergic receptor (A... BeFree 11576322 Detail
0.079 Diabetes Mellitus, Non-Insulin-Dependent The presence of at least three alleles of the ADRB3 Trp64Arg (C/T) and UCP1 -382... BeFree 24138564 Detail
0.029 Metabolic syndrome X A possible pathogenic mutation in the beta 3-adrenergic-receptor gene (Trp64Arg)... BeFree 8721782 Detail
0.003 hyperuricemia Trp64Arg (rs4994) polymorphism of β3-adrenergic receptor gene is associated with... BeFree 23729572 Detail
0.003 hyperuricemia Trp64Arg polymorphism of the ADRB3 gene predicts hyperuricemia risk in a populat... BeFree 20008926 Detail
0.029 Metabolic syndrome X We recently identified a mutation in the human beta 3-adrenergic receptor (beta ... BeFree 8923875 Detail
0.003 Obesity, Abdominal The Trp64Arg allele of the beta 3-adrenergic receptor is associated with abdomin... BeFree 7609751 Detail
0.006 coronary artery disease Significant role of ADRB3 rs4994 towards the development of coronary artery dise... BeFree 24201118 Detail
0.343 obesity Phenotypic characterization of the Trp64Arg polymorphism in the beta 3-adrenergi... BeFree 8817112 Detail
0.001 Dyslipidemias The Trp64Arg mutation of the beta 3-adrenergic receptor (beta 3AR) is prevalent ... BeFree 9112025 Detail
<0.001 Impaired glucose tolerance Trp64Arg mutation of beta 3-adrenergic receptor and insulin sensitivity in subje... BeFree 9313101 Detail
0.343 obesity A missense mutation of the human ADRB3 gene replacing tryptophan with arginine a... BeFree 18088254 Detail
0.079 Diabetes Mellitus, Non-Insulin-Dependent Some studies indicate that the Trp64Arg polymorphism in the gene encoding the be... BeFree 18335327 Detail
0.003 Overweight The presence of at least three alleles of the ADRB3 Trp64Arg (C/T) and UCP1 -382... BeFree 24138564 Detail
0.003 hyperandrogenism No association between body mass index and beta(3)-adrenergic receptor variant (... BeFree 10689004 Detail
0.020 Diabetes Mellitus, Non-Insulin-Dependent The presence of at least three alleles of the ADRB3 Trp64Arg (C/T) and UCP1 -382... BeFree 24138564 Detail
0.343 obesity The Trp64Arg polymorphism of ADRB3 seems to not be related to obesity in postmen... BeFree 17852419 Detail
0.343 obesity To establish the influence of the Trp64Arg variant of the beta3-adrenergic recep... BeFree 18422027 Detail
0.079 Diabetes Mellitus, Non-Insulin-Dependent The Trp64Arg allele of the beta 3-AR gene was significantly more frequent in the... BeFree 9313761 Detail
0.343 obesity The Trp64Arg polymorphism of ADRB3 warrants consideration, along with other poly... BeFree 16276029 Detail
0.343 obesity TRP64ARG polymorphism of the beta 3-adrenergic receptor gene and obesity risk: e... BeFree 12406043 Detail
0.343 obesity The ADRB3 Trp64Arg variant and obesity in African-American breast cancer cases. BeFree 17264845 Detail
0.003 gestational diabetes Our results indicated that the ADRB3 Trp64Arg variant is not related to the deve... BeFree 15334374 Detail
0.343 obesity TRP64ARG beta 3-adrenergic receptor and obesity in Mexican Americans. BeFree 9439659 Detail
0.001 Overweight The presence of at least three alleles of the ADRB3 Trp64Arg (C/T) and UCP1 -382... BeFree 24138564 Detail
0.343 obesity Some studies indicate that the Trp64Arg polymorphism in the gene encoding the be... BeFree 18335327 Detail
0.006 Coronary heart disease Significant role of ADRB3 rs4994 towards the development of coronary artery dise... BeFree 24201118 Detail
0.343 obesity NA CLINVAR Detail
<0.001 obesity To determine whether this SNP affects insulin resistance syndrome associated wit... BeFree 12965109 Detail
0.079 Diabetes Mellitus, Non-Insulin-Dependent In contrast, the non-synonymous ADRB3 rs4994 polymorphism is associated with T2D... BeFree 20503258 Detail
0.029 Metabolic syndrome X In contrast, the non-synonymous ADRB3 rs4994 polymorphism is associated with T2D... BeFree 20503258 Detail
0.343 obesity The results of the present study suggest that the Trp64Arg mutation of the beta(... BeFree 12917707 Detail
0.440 obesity Trp64Arg polymorphism of the beta 3-adrenergic receptor gene is associated with ... BeFree 10502846 Detail
0.079 Diabetes Mellitus, Non-Insulin-Dependent These present findings show that the Trp64Arg allele of the beta 3-adrenergic re... BeFree 9405912 Detail
0.164 obesity The presence of at least three alleles of the ADRB3 Trp64Arg (C/T) and UCP1 -382... BeFree 24138564 Detail
0.003 Coronary Arteriosclerosis Significant role of ADRB3 rs4994 towards the development of coronary artery dise... BeFree 24201118 Detail
0.343 obesity The beta(3)-adrenergic receptor (AR) gene variant (Trp64Arg) has been reported t... BeFree 11288039 Detail
0.085 polycystic ovary syndrome To determine if the Trp(64)Arg (W64R) variant of the beta(3)-adrenergic receptor... BeFree 10689004 Detail
0.002 Insulin resistance syndrome A possible pathogenic mutation in the beta 3-adrenergic-receptor gene (Trp64Arg)... BeFree 8721782 Detail
0.001 essential hypertension Among the six genes related to RAAS, the frequencies of rs4994 (ADRB3) and rs519... BeFree 25099490 Detail
0.002 Insulin resistance syndrome We recently identified a mutation in the human beta 3-adrenergic receptor (beta ... BeFree 8923875 Detail
0.231 obesity In conclusion, the frequency of the Trp64Arg mutation of the beta 3-AR was highe... BeFree 9315379 Detail
0.079 Diabetes Mellitus, Non-Insulin-Dependent The tryptophan to arginine change in position 64 (Trp64Arg) polymorphism of the ... BeFree 16634992 Detail
0.001 essential hypertension Association of Trp64Arg beta 3-adrenergic-receptor gene polymorphism with essent... BeFree 10100091 Detail
0.047 Hypertensive disease A missense mutation of the human ADRB3 gene replacing tryptophan with arginine a... BeFree 18088254 Detail
0.343 obesity The functional variant Trp64Arg in the beta(3)-adrenergic receptor has previousl... BeFree 18249022 Detail
0.343 obesity Allele frequency of Trp64Arg variation in the beta(3)AR gene in the obese subjec... BeFree 17445027 Detail
0.079 Diabetes Mellitus, Non-Insulin-Dependent The Trp64Arg beta3AR variant is associated in some, but not all, studies with an... BeFree 10441039 Detail
0.079 Diabetes Mellitus, Non-Insulin-Dependent The Trp64Arg allele of the beta 3-adrenergic receptor is associated with abdomin... BeFree 7609751 Detail
0.343 obesity The beta(3)-adrenergic receptor TRP64ARG polymorphism and obesity in Alaskan Esk... BeFree 9426386 Detail
0.002 Insulin resistance syndrome The Trp64Arg polymorphism of the beta 3-Adrenergic receptor gene. Lack of associ... BeFree 9250462 Detail
0.008 Obesity, Morbid To evaluate the prevalence of beta(3)-adrenergic receptor (ADRB3) Trp64Arg polym... BeFree 17299491 Detail
0.343 obesity The beta 3-adrenergic receptor gene Trp64Arg mutation is overrepresented in obes... BeFree 8826971 Detail
0.006 coronary artery disease Beta 3 adrenergic receptor Trp64Arg polymorphism and manifestation of coronary a... BeFree 16715838 Detail
0.374 Diabetes Mellitus, Non-Insulin-Dependent We investigated the relationship between the Trp64Arg mutation in the beta 3-adr... BeFree 9313101 Detail
0.343 obesity The aim of our study was to investigate the role of Trp64Arg polymorphism of the... BeFree 23736006 Detail
0.343 obesity To determine whether this SNP affects insulin resistance syndrome associated wit... BeFree 12965109 Detail
0.003 hyperuricemia The association between hyperuricemia and the Trp64Arg polymorphism of the beta-... BeFree 17225053 Detail
0.002 Insulin resistance syndrome The Trp64Arg beta3AR variant is associated in some, but not all, studies with an... BeFree 10441039 Detail
0.343 obesity The risk of obesity and the Trp64Arg polymorphism of the beta(3)-adrenergic rece... BeFree 12169859 Detail
0.002 Insulin resistance syndrome To determine whether this SNP affects insulin resistance syndrome associated wit... BeFree 12965109 Detail
0.017 Cardiovascular Diseases A cross-sectional investigation of 877 Japanese men and women (18-75 years old) ... BeFree 24658877 Detail
0.002 diabetes mellitus A tryptophan to arginine (Trp64Arg) mutation in the beta 3-adrenergic receptor (... BeFree 8826971 Detail
0.029 Metabolic syndrome X Trp64Arg polymorphism of the ADRB3 gene may affect VF accumulation and be associ... BeFree 23282015 Detail
<0.001 breast carcinoma To determine if a missense change at codon 64 of ADRB3 (Trp64Arg), a candidate o... BeFree 17264845 Detail
0.034 Diabetes Mellitus, Non-Insulin-Dependent Effect of the combination of the variants -75G/A APOA1 and Trp64Arg ADRB3 on the... BeFree 17727676 Detail
0.029 Metabolic syndrome X The Trp64Arg beta3AR variant is associated in some, but not all, studies with an... BeFree 10441039 Detail
0.343 obesity These findings do not support the view that there is an association between the ... BeFree 8903328 Detail
0.002 Diabetes β3-Adrenergic receptor (ADRB3) Trp64Arg polymorphism is associated with atheroge... BeFree 24658877 Detail
0.079 Diabetes Mellitus, Non-Insulin-Dependent Recently, a missense mutation replacing tryptophan with arginine at codon 64 of ... BeFree 8690160 Detail
0.006 Coronary heart disease Beta 3 adrenergic receptor Trp64Arg polymorphism and manifestation of coronary a... BeFree 16715838 Detail
0.003 hyperuricemia The common polymorphism rs4994 [c. T387C, p. Trp64Arg (W64R)] of the lipolysis r... BeFree 21285172 Detail
0.343 obesity Molecular screening of the ADRB3 gene polymorphism (Trp64Trp, Trp64Arg and Arg64... BeFree 23282015 Detail
0.079 Diabetes Mellitus, Non-Insulin-Dependent The Trp64Arg polymorphism in the beta3AR gene has been reported to be associated... BeFree 15743038 Detail
0.079 Diabetes Mellitus, Non-Insulin-Dependent Genotype Arg/Arg, but not Trp/Arg, of the Trp64Arg polymorphism of the beta(3)-a... BeFree 11522702 Detail
0.343 obesity Relation of Trp64Arg polymorphism of beta 3-adrenergic receptor gene to adipocyt... BeFree 18617734 Detail
<0.001 chronic interstitial cystitis We analyzed 5 gene polymorphisms (G404781T, Arg16Gly, Trp64Arg, C589T and Ile50V... BeFree 12442007 Detail
0.079 Diabetes Mellitus, Non-Insulin-Dependent We investigated the relationship between the Trp64Arg mutation in the beta 3-adr... BeFree 9313101 Detail
0.343 obesity Expression of the beta 3-adrenoceptor gene polymorphism (Trp64Arg) in obese diab... BeFree 9315379 Detail
0.002 diabetes mellitus β3-Adrenergic receptor (ADRB3) Trp64Arg polymorphism is associated with atheroge... BeFree 24658877 Detail
0.002 Diabetes A tryptophan to arginine (Trp64Arg) mutation in the beta 3-adrenergic receptor (... BeFree 8826971 Detail
0.079 Diabetes Mellitus, Non-Insulin-Dependent A missense mutation of the human ADRB3 gene replacing tryptophan with arginine a... BeFree 18088254 Detail
0.343 obesity Our results indicated that the ADRB3 Trp64Arg variant is not related to the deve... BeFree 15334374 Detail
0.079 Diabetes Mellitus, Non-Insulin-Dependent The beta(3)-adrenergic receptor gene (BAR-3) allelic variant (Trp64Arg and Arg64... BeFree 12943691 Detail
0.003 Obesity, Abdominal In conclusion, the Trp64Arg polymorphism of the beta 3-adrenergic receptor gene ... BeFree 17087055 Detail
0.029 Metabolic syndrome X To determine whether this SNP affects insulin resistance syndrome associated wit... BeFree 12965109 Detail
0.343 obesity The Trp64Arg polymorphism of the beta(3)-adrenergic receptor (beta(3)-AR) gene i... BeFree 17998022 Detail
0.343 obesity The presence of at least three alleles of the ADRB3 Trp64Arg (C/T) and UCP1 -382... BeFree 24138564 Detail
<0.001 diabetes mellitus In Cox regression model, after adjustment for baseline confounding variables inc... BeFree 20536507 Detail
0.002 diabetes mellitus In Cox regression model, after adjustment for baseline confounding variables inc... BeFree 20536507 Detail
<0.001 Diabetes In Cox regression model, after adjustment for baseline confounding variables inc... BeFree 20536507 Detail
0.002 Diabetes In Cox regression model, after adjustment for baseline confounding variables inc... BeFree 20536507 Detail
0.001 Diabetes In Cox regression model, after adjustment for baseline confounding variables inc... BeFree 20536507 Detail
0.002 diabetes mellitus In Cox regression model, after adjustment for baseline confounding variables inc... BeFree 20536507 Detail
Annotation

Annotations

DescrptionSourceLinks
NM_000025.3(ADRB3):c.190T>C (p.Trp64Arg) AND Obesity ClinVar Detail
NM_000025.3(ADRB3):c.190T>C (p.Trp64Arg) AND not provided ClinVar Detail
Several common single nucleotide polymorphisms (SNPs) including Gly389Arg in beta(1)-AR, Gln27Glu in... DisGeNET Detail
Several common single nucleotide polymorphisms (SNPs) including Gly389Arg in beta(1)-AR, Gln27Glu in... DisGeNET Detail
Several common single nucleotide polymorphisms (SNPs) including Gly389Arg in beta(1)-AR, Gln27Glu in... DisGeNET Detail
We analyzed the obesity-related phenotypes body mass index (BMI), percentage of body fat, plasma lep... DisGeNET Detail
We analyzed the obesity-related phenotypes body mass index (BMI), percentage of body fat, plasma lep... DisGeNET Detail
We analyzed the obesity-related phenotypes body mass index (BMI), percentage of body fat, plasma lep... DisGeNET Detail
We analyzed the obesity-related phenotypes body mass index (BMI), percentage of body fat, plasma lep... DisGeNET Detail
We analyzed the obesity-related phenotypes body mass index (BMI), percentage of body fat, plasma lep... DisGeNET Detail
We analyzed the obesity-related phenotypes body mass index (BMI), percentage of body fat, plasma lep... DisGeNET Detail
We analyzed the obesity-related phenotypes body mass index (BMI), percentage of body fat, plasma lep... DisGeNET Detail
Under an additive genetic model, the C allele of ADRB3-rs4994, the C allele of ENPP1-rs1044498, and ... DisGeNET Detail
Under an additive genetic model, the C allele of ADRB3-rs4994, the C allele of ENPP1-rs1044498, and ... DisGeNET Detail
Under an additive genetic model, the C allele of ADRB3-rs4994, the C allele of ENPP1-rs1044498, and ... DisGeNET Detail
We genotyped 7 single-nucleotide polymorphisms (SNPs) in PPARG2 (rs1801282), ADIPOQ (rs1501299), ADR... DisGeNET Detail
We genotyped 7 single-nucleotide polymorphisms (SNPs) in PPARG2 (rs1801282), ADIPOQ (rs1501299), ADR... DisGeNET Detail
We genotyped 7 single-nucleotide polymorphisms (SNPs) in PPARG2 (rs1801282), ADIPOQ (rs1501299), ADR... DisGeNET Detail
We genotyped 7 single-nucleotide polymorphisms (SNPs) in PPARG2 (rs1801282), ADIPOQ (rs1501299), ADR... DisGeNET Detail
We genotyped 7 single-nucleotide polymorphisms (SNPs) in PPARG2 (rs1801282), ADIPOQ (rs1501299), ADR... DisGeNET Detail
We genotyped 7 single-nucleotide polymorphisms (SNPs) in PPARG2 (rs1801282), ADIPOQ (rs1501299), ADR... DisGeNET Detail
We genotyped 7 single-nucleotide polymorphisms (SNPs) in PPARG2 (rs1801282), ADIPOQ (rs1501299), ADR... DisGeNET Detail
We genotyped 7 single-nucleotide polymorphisms (SNPs) in PPARG2 (rs1801282), ADIPOQ (rs1501299), ADR... DisGeNET Detail
We genotyped 7 single-nucleotide polymorphisms (SNPs) in PPARG2 (rs1801282), ADIPOQ (rs1501299), ADR... DisGeNET Detail
We genotyped 7 single-nucleotide polymorphisms (SNPs) in PPARG2 (rs1801282), ADIPOQ (rs1501299), ADR... DisGeNET Detail
In conclusion, no major difference was associated with the beta3AR Trp64Arg or FABP2 Ala54Thr polymo... DisGeNET Detail
In conclusion, no major difference was associated with the beta3AR Trp64Arg or FABP2 Ala54Thr polymo... DisGeNET Detail
In conclusion, no major difference was associated with the beta3AR Trp64Arg or FABP2 Ala54Thr polymo... DisGeNET Detail
In conclusion, no major difference was associated with the beta3AR Trp64Arg or FABP2 Ala54Thr polymo... DisGeNET Detail
These data demonstrated that ADRB3 rs4994 and CYP11B2 rs1799998 were significantly closely associate... DisGeNET Detail
These data demonstrated that ADRB3 rs4994 and CYP11B2 rs1799998 were significantly closely associate... DisGeNET Detail
We investigated whether the -3826A/G polymorphism (rs1800592) of the uncoupling protein 1 gene (UCP1... DisGeNET Detail
We investigated whether the -3826A/G polymorphism (rs1800592) of the uncoupling protein 1 gene (UCP1... DisGeNET Detail
The objective of this work was to analyze the association of polymorphisms in ADRB1 (rs1801253) (Arg... DisGeNET Detail
The objective of this work was to analyze the association of polymorphisms in ADRB1 (rs1801253) (Arg... DisGeNET Detail
The ADRB3 Trp64Arg variant is a susceptibility gene polymorphism for T2D and the ADRB1 Gly389Arg for... DisGeNET Detail
The ADRB3 Trp64Arg variant is a susceptibility gene polymorphism for T2D and the ADRB1 Gly389Arg for... DisGeNET Detail
We studied possible relations between GDM and both insulin receptor substrate 1 (IRS-1) (Gly972Arg) ... DisGeNET Detail
We studied possible relations between GDM and both insulin receptor substrate 1 (IRS-1) (Gly972Arg) ... DisGeNET Detail
The other polymorphisms studied were not significantly associated with gestational diabetes mellitus... DisGeNET Detail
The other polymorphisms studied were not significantly associated with gestational diabetes mellitus... DisGeNET Detail
The other polymorphisms studied were not significantly associated with gestational diabetes mellitus... DisGeNET Detail
Beta3AR Trp64Arg and PPARgamma2 Pro12Ala polymorphisms might be associated with insulin resistance a... DisGeNET Detail
The other polymorphisms studied were not significantly associated with gestational diabetes mellitus... DisGeNET Detail
Beta3AR Trp64Arg and PPARgamma2 Pro12Ala polymorphisms might be associated with insulin resistance a... DisGeNET Detail
The other polymorphisms studied were not significantly associated with gestational diabetes mellitus... DisGeNET Detail
Possible impact of ADRB3 Trp64Arg polymorphism on BMI in patients with schizophrenia. DisGeNET Detail
The β3-adrenoceptor (ADRB3) gene Trp64Arg polymorphism has been shown to be associated with obesity ... DisGeNET Detail
Some studies indicate that the Trp64Arg polymorphism in the gene encoding the beta3-adrenergic recep... DisGeNET Detail
The Trp64Arg allele of the beta 3-adrenergic receptor is associated with abdominal obesity and resis... DisGeNET Detail
Our results suggest that obese postmenopausal women who are heterozygous for the Trp64Arg variant in... DisGeNET Detail
In this study, the prevalence of the Trp64Arg ADRB3 polymorphism in a large group of patients with O... DisGeNET Detail
Lack of association between the Trp64 Arg mutation in the beta 3-adrenergic receptor gene and obesit... DisGeNET Detail
Our results indicate that the ADRB3 Trp64Arg polymorphism is associated with gallstone disease there... DisGeNET Detail
The Trp64Arg mutation of the beta 3-adrenergic receptor (beta 3AR) is prevalent in several ethnic gr... DisGeNET Detail
Relationship between Trp64Arg mutation in the β3-adrenergic receptor gene and metabolic syndrome: a ... DisGeNET Detail
The association between the tryptophan 64 arginine polymorphism in the beta(3)-AR gene and idiopathi... DisGeNET Detail
The Trp64Arg polymorphism of the beta 3-Adrenergic receptor gene. Lack of association with NIDDM and... DisGeNET Detail
Our results suggest that the Trp64Arg mutation is not a major determinant of metabolic disorders (ty... DisGeNET Detail
In summary, we found that obese postmenopausal women who carry the Trp64Arg variant in the beta(3)-a... DisGeNET Detail
The Trp64Arg allele of the beta 3-adrenergic receptor is associated with abdominal obesity and resis... DisGeNET Detail
The β3-adrenoceptor (ADRB3) gene Trp64Arg polymorphism has been shown to be associated with obesity ... DisGeNET Detail
The tryptophan to arginine change in position 64 (Trp64Arg) polymorphism of the beta3-adrenergic rec... DisGeNET Detail
We obtained no evidence for the association of ADRB3 Trp64Arg with the development of MDD or schizop... DisGeNET Detail
The Trp64Arg polymorphism of the beta 3-Adrenergic receptor gene. Lack of association with NIDDM and... DisGeNET Detail
The aim of our study was to investigate the interaction of tryptophan-to-arginine (Trp64Arg) missens... DisGeNET Detail
It has been shown that the β3-adrenergic receptor (β3-AR) gene Trp64Arg mutation was closely related... DisGeNET Detail
We obtained no evidence for the association of ADRB3 Trp64Arg with the development of MDD or schizop... DisGeNET Detail
The beta(3)-adrenergic receptor gene (BAR-3) allelic variant (Trp64Arg and Arg64Arg) is correlated w... DisGeNET Detail
The relationship between the Trp 64 Arg polymorphism of the beta 3-adrenoceptor gene and idiopathic ... DisGeNET Detail
As the presence of a Trp64Arg polymorphism of the gene encoding the β(3)-adrenoceptor (B3AR) has bee... DisGeNET Detail
In conclusion, the Trp64Arg polymorphism of the beta 3-adrenergic receptor gene is associated with o... DisGeNET Detail
These data suggest that the Trp64Arg mutation not only contributes to weight gain and age-at-onset o... DisGeNET Detail
To determine whether this SNP affects insulin resistance syndrome associated with type 2 diabetes, w... DisGeNET Detail
To determine if a missense change at codon 64 of ADRB3 (Trp64Arg), a candidate obesity gene, is asso... DisGeNET Detail
Genotype Arg/Arg, but not Trp/Arg, of the Trp64Arg polymorphism of the beta(3)-adrenergic receptor i... DisGeNET Detail
The Trp64Arg allele of the beta 3-AR gene was significantly more frequent in the NIDDM patients with... DisGeNET Detail
Gender effect of the Trp64Arg mutation in the beta 3 adrenergic receptor gene on weight gain in morb... DisGeNET Detail
Our results are consistent with the thesis that the Trp64Arg polymorphism of the beta 3-adrenergic r... DisGeNET Detail
Additive effect of A--&gt;G (-3826) variant of the uncoupling protein gene and the Trp64Arg mutation... DisGeNET Detail
Our results indicate that the ADRB3 Trp64Arg polymorphism is associated with gallstone disease there... DisGeNET Detail
We have investigated whether the Trp64Arg polymorphism of the beta 3-AR was associated with body mas... DisGeNET Detail
Effect of the combination of the variants -75G/A APOA1 and Trp64Arg ADRB3 on the risk of type 2 diab... DisGeNET Detail
We analyzed 5 gene polymorphisms (G404781T, Arg16Gly, Trp64Arg, C589T and Ile50Val) per gene (ADRA1d... DisGeNET Detail
Beta 3 adrenergic receptor Trp64Arg polymorphism and manifestation of coronary artery disease in Ara... DisGeNET Detail
In conclusion, the Trp64Arg polymorphism of the beta 3-adrenergic receptor gene is associated with o... DisGeNET Detail
Trp64Arg polymorphism of the beta 3-adrenergic receptor gene is associated with increased plasma lep... DisGeNET Detail
In conclusion, the frequency of the Trp64Arg mutation of the beta 3-AR was higher in this obese popu... DisGeNET Detail
In the crude analysis, hypothesis tests and odds ratios show that there is no evidence of associatio... DisGeNET Detail
Trp64Arg mutation of beta 3-adrenergic receptor and insulin sensitivity in subjects with glucose int... DisGeNET Detail
To investigate the association between the Trp64Arg beta3-adrenergic receptor (ADRB3) mutation and o... DisGeNET Detail
The presence of at least three alleles of the ADRB3 Trp64Arg (C/T) and UCP1 -3826A/G polymorphisms i... DisGeNET Detail
A possible pathogenic mutation in the beta 3-adrenergic-receptor gene (Trp64Arg) has been reported t... DisGeNET Detail
Trp64Arg (rs4994) polymorphism of β3-adrenergic receptor gene is associated with hyperuricemia in a ... DisGeNET Detail
Trp64Arg polymorphism of the ADRB3 gene predicts hyperuricemia risk in a population from southern Sp... DisGeNET Detail
We recently identified a mutation in the human beta 3-adrenergic receptor (beta 3AR) gene (codon 64 ... DisGeNET Detail
The Trp64Arg allele of the beta 3-adrenergic receptor is associated with abdominal obesity and resis... DisGeNET Detail
Significant role of ADRB3 rs4994 towards the development of coronary artery disease. DisGeNET Detail
Phenotypic characterization of the Trp64Arg polymorphism in the beta 3-adrenergic receptor gene in n... DisGeNET Detail
The Trp64Arg mutation of the beta 3-adrenergic receptor (beta 3AR) is prevalent in several ethnic gr... DisGeNET Detail
Trp64Arg mutation of beta 3-adrenergic receptor and insulin sensitivity in subjects with glucose int... DisGeNET Detail
A missense mutation of the human ADRB3 gene replacing tryptophan with arginine at codon 64 (Trp64Arg... DisGeNET Detail
Some studies indicate that the Trp64Arg polymorphism in the gene encoding the beta(3)-adrenergic rec... DisGeNET Detail
The presence of at least three alleles of the ADRB3 Trp64Arg (C/T) and UCP1 -3826A/G polymorphisms i... DisGeNET Detail
No association between body mass index and beta(3)-adrenergic receptor variant (W64R) in children wi... DisGeNET Detail
The presence of at least three alleles of the ADRB3 Trp64Arg (C/T) and UCP1 -3826A/G polymorphisms i... DisGeNET Detail
The Trp64Arg polymorphism of ADRB3 seems to not be related to obesity in postmenopausal women. DisGeNET Detail
To establish the influence of the Trp64Arg variant of the beta3-adrenergic receptor (Trp64Arg- beta3... DisGeNET Detail
The Trp64Arg allele of the beta 3-AR gene was significantly more frequent in the NIDDM patients with... DisGeNET Detail
The Trp64Arg polymorphism of ADRB3 warrants consideration, along with other polymorphisms involved i... DisGeNET Detail
TRP64ARG polymorphism of the beta 3-adrenergic receptor gene and obesity risk: effect modification b... DisGeNET Detail
The ADRB3 Trp64Arg variant and obesity in African-American breast cancer cases. DisGeNET Detail
Our results indicated that the ADRB3 Trp64Arg variant is not related to the development of GDM and h... DisGeNET Detail
TRP64ARG beta 3-adrenergic receptor and obesity in Mexican Americans. DisGeNET Detail
The presence of at least three alleles of the ADRB3 Trp64Arg (C/T) and UCP1 -3826A/G polymorphisms i... DisGeNET Detail
Some studies indicate that the Trp64Arg polymorphism in the gene encoding the beta(3)-adrenergic rec... DisGeNET Detail
Significant role of ADRB3 rs4994 towards the development of coronary artery disease. DisGeNET Detail
NA DisGeNET Detail
To determine whether this SNP affects insulin resistance syndrome associated with type 2 diabetes, w... DisGeNET Detail
In contrast, the non-synonymous ADRB3 rs4994 polymorphism is associated with T2D and MS. DisGeNET Detail
In contrast, the non-synonymous ADRB3 rs4994 polymorphism is associated with T2D and MS. DisGeNET Detail
The results of the present study suggest that the Trp64Arg mutation of the beta(3)AR gene is associa... DisGeNET Detail
Trp64Arg polymorphism of the beta 3-adrenergic receptor gene is associated with increased plasma lep... DisGeNET Detail
These present findings show that the Trp64Arg allele of the beta 3-adrenergic receptor gene may pred... DisGeNET Detail
The presence of at least three alleles of the ADRB3 Trp64Arg (C/T) and UCP1 -3826A/G polymorphisms i... DisGeNET Detail
Significant role of ADRB3 rs4994 towards the development of coronary artery disease. DisGeNET Detail
The beta(3)-adrenergic receptor (AR) gene variant (Trp64Arg) has been reported to be associated with... DisGeNET Detail
To determine if the Trp(64)Arg (W64R) variant of the beta(3)-adrenergic receptor (ADRB3) could be us... DisGeNET Detail
A possible pathogenic mutation in the beta 3-adrenergic-receptor gene (Trp64Arg) has been reported t... DisGeNET Detail
Among the six genes related to RAAS, the frequencies of rs4994 (ADRB3) and rs5194 (AGTR2) were found... DisGeNET Detail
We recently identified a mutation in the human beta 3-adrenergic receptor (beta 3AR) gene (codon 64 ... DisGeNET Detail
In conclusion, the frequency of the Trp64Arg mutation of the beta 3-AR was higher in this obese popu... DisGeNET Detail
The tryptophan to arginine change in position 64 (Trp64Arg) polymorphism of the beta3-adrenergic rec... DisGeNET Detail
Association of Trp64Arg beta 3-adrenergic-receptor gene polymorphism with essential hypertension in ... DisGeNET Detail
A missense mutation of the human ADRB3 gene replacing tryptophan with arginine at codon 64 (Trp64Arg... DisGeNET Detail
The functional variant Trp64Arg in the beta(3)-adrenergic receptor has previously been examined for ... DisGeNET Detail
Allele frequency of Trp64Arg variation in the beta(3)AR gene in the obese subjects was 0.16, which i... DisGeNET Detail
The Trp64Arg beta3AR variant is associated in some, but not all, studies with an earlier onset of Ty... DisGeNET Detail
The Trp64Arg allele of the beta 3-adrenergic receptor is associated with abdominal obesity and resis... DisGeNET Detail
The beta(3)-adrenergic receptor TRP64ARG polymorphism and obesity in Alaskan Eskimos. DisGeNET Detail
The Trp64Arg polymorphism of the beta 3-Adrenergic receptor gene. Lack of association with NIDDM and... DisGeNET Detail
To evaluate the prevalence of beta(3)-adrenergic receptor (ADRB3) Trp64Arg polymorphism and its rela... DisGeNET Detail
The beta 3-adrenergic receptor gene Trp64Arg mutation is overrepresented in obese women. Effects on ... DisGeNET Detail
Beta 3 adrenergic receptor Trp64Arg polymorphism and manifestation of coronary artery disease in Ara... DisGeNET Detail
We investigated the relationship between the Trp64Arg mutation in the beta 3-adrenergic receptor gen... DisGeNET Detail
The aim of our study was to investigate the role of Trp64Arg polymorphism of the beta 3-adrenergic r... DisGeNET Detail
To determine whether this SNP affects insulin resistance syndrome associated with type 2 diabetes, w... DisGeNET Detail
The association between hyperuricemia and the Trp64Arg polymorphism of the beta-3 adrenergic recepto... DisGeNET Detail
The Trp64Arg beta3AR variant is associated in some, but not all, studies with an earlier onset of Ty... DisGeNET Detail
The risk of obesity and the Trp64Arg polymorphism of the beta(3)-adrenergic receptor: effect modific... DisGeNET Detail
To determine whether this SNP affects insulin resistance syndrome associated with type 2 diabetes, w... DisGeNET Detail
A cross-sectional investigation of 877 Japanese men and women (18-75 years old) was performed to cla... DisGeNET Detail
A tryptophan to arginine (Trp64Arg) mutation in the beta 3-adrenergic receptor (beta 3-AR) gene has ... DisGeNET Detail
Trp64Arg polymorphism of the ADRB3 gene may affect VF accumulation and be associated with MS, a clus... DisGeNET Detail
To determine if a missense change at codon 64 of ADRB3 (Trp64Arg), a candidate obesity gene, is asso... DisGeNET Detail
Effect of the combination of the variants -75G/A APOA1 and Trp64Arg ADRB3 on the risk of type 2 diab... DisGeNET Detail
The Trp64Arg beta3AR variant is associated in some, but not all, studies with an earlier onset of Ty... DisGeNET Detail
These findings do not support the view that there is an association between the Trp64Arg mutation in... DisGeNET Detail
β3-Adrenergic receptor (ADRB3) Trp64Arg polymorphism is associated with atherogenic risk factors tha... DisGeNET Detail
Recently, a missense mutation replacing tryptophan with arginine at codon 64 of the beta 3-adrenergi... DisGeNET Detail
Beta 3 adrenergic receptor Trp64Arg polymorphism and manifestation of coronary artery disease in Ara... DisGeNET Detail
The common polymorphism rs4994 [c. T387C, p. Trp64Arg (W64R)] of the lipolysis regulator beta-3-adre... DisGeNET Detail
Molecular screening of the ADRB3 gene polymorphism (Trp64Trp, Trp64Arg and Arg64Arg) was carried out... DisGeNET Detail
The Trp64Arg polymorphism in the beta3AR gene has been reported to be associated with insulin resist... DisGeNET Detail
Genotype Arg/Arg, but not Trp/Arg, of the Trp64Arg polymorphism of the beta(3)-adrenergic receptor i... DisGeNET Detail
Relation of Trp64Arg polymorphism of beta 3-adrenergic receptor gene to adipocytokines and fat distr... DisGeNET Detail
We analyzed 5 gene polymorphisms (G404781T, Arg16Gly, Trp64Arg, C589T and Ile50Val) per gene (ADRA1d... DisGeNET Detail
We investigated the relationship between the Trp64Arg mutation in the beta 3-adrenergic receptor gen... DisGeNET Detail
Expression of the beta 3-adrenoceptor gene polymorphism (Trp64Arg) in obese diabetic and non-diabeti... DisGeNET Detail
β3-Adrenergic receptor (ADRB3) Trp64Arg polymorphism is associated with atherogenic risk factors tha... DisGeNET Detail
A tryptophan to arginine (Trp64Arg) mutation in the beta 3-adrenergic receptor (beta 3-AR) gene has ... DisGeNET Detail
A missense mutation of the human ADRB3 gene replacing tryptophan with arginine at codon 64 (Trp64Arg... DisGeNET Detail
Our results indicated that the ADRB3 Trp64Arg variant is not related to the development of GDM and h... DisGeNET Detail
The beta(3)-adrenergic receptor gene (BAR-3) allelic variant (Trp64Arg and Arg64Arg) is correlated w... DisGeNET Detail
In conclusion, the Trp64Arg polymorphism of the beta 3-adrenergic receptor gene is associated with o... DisGeNET Detail
To determine whether this SNP affects insulin resistance syndrome associated with type 2 diabetes, w... DisGeNET Detail
The Trp64Arg polymorphism of the beta(3)-adrenergic receptor (beta(3)-AR) gene is a genetic marker f... DisGeNET Detail
The presence of at least three alleles of the ADRB3 Trp64Arg (C/T) and UCP1 -3826A/G polymorphisms i... DisGeNET Detail
In Cox regression model, after adjustment for baseline confounding variables including age, sex, smo... DisGeNET Detail
In Cox regression model, after adjustment for baseline confounding variables including age, sex, smo... DisGeNET Detail
In Cox regression model, after adjustment for baseline confounding variables including age, sex, smo... DisGeNET Detail
In Cox regression model, after adjustment for baseline confounding variables including age, sex, smo... DisGeNET Detail
In Cox regression model, after adjustment for baseline confounding variables including age, sex, smo... DisGeNET Detail
In Cox regression model, after adjustment for baseline confounding variables including age, sex, smo... DisGeNET Detail

Overlapped Transcript Coordinates

Gene Transcript ID Exon Number Chromosome Start Stop Type Amino Mutation Transcript Position Links

Overlapped Transcript

Gene Transcript ID Chromosome Start Stop Links
Gene
-
dbSNP
rs4994 dbSNP
Genome
hg19
Position
chr8:37,823,798-37,823,798
Variant Type
snv
Reference Allele
A
Alternative Allele
G
Filtering Status (HGVD)
PASS
# of samples (HGVD)
1195
Mean of sample read depth (HGVD)
75.94
Standard deviation of sample read depth (HGVD)
37.18
Number of reference allele (HGVD)
1965
Number of alternative allele (HGVD)
425
Allele Frequency (HGVD)
0.17782426778242677
Gene Symbol (HGVD)
ADRB3
ToMMo VCF FILTER column value (ToMMo 8.3KJPN Allele Frequency Panel(v20200831))
PASS
Total VCF ID column value (ToMMo 8.3KJPN Allele Frequency Panel(v20200831))
rs4994
Allele frequency, for each ALT allele (ToMMo 8.3KJPN Allele Frequency Panel(v20200831))
0.1922
Allele count in genotypes, for each ALT allele (ToMMo 8.3KJPN Allele Frequency Panel(v20200831))
3220
Total number of alleles in called genotypes (ToMMo 8.3KJPN Allele Frequency Panel(v20200831))
16754
East Asian Chromosome Counts (ExAC)
8408
East Asian Allele Counts (ExAC)
1214
East Asian Heterozygous Counts (ExAC)
1040
East Asian Homozygous Counts (ExAC)
87
East Asian Allele Frequency (ExAC)
0.1443862987630828
Chromosome Counts in All Race (ExAC)
115984
Allele Counts in All Race (ExAC)
12257
Heterozygous Counts in All Race (ExAC)
10663
Homozygous Counts in All Race (ExAC)
797
Allele Frequency in All Race (ExAC)
0.10567836943026625
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